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Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA

The spliceosome removes introns from precursor messenger RNA (pre-mRNA) to produce mature mRNA. Prior to catalysis, spliceosomes are assembled de novo onto pre-mRNA substrates. During this assembly process, U6 small nuclear RNA (snRNA) undergoes extensive structural remodeling. The early stages of t...

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Detalles Bibliográficos
Autores principales:	Montemayor, Eric J., Didychuk, Allison L., Yake, Allyson D., Sidhu, Gurnimrat K., Brow, David A., Butcher, Samuel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931518/ https://www.ncbi.nlm.nih.gov/pubmed/29717126 http://dx.doi.org/10.1038/s41467-018-04145-4

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