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Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy

Age-related muscle atrophy (sarcopenia) is the leading cause for disability in aged population, but the underlying molecular mechanisms are poorly understood. Here we identify a novel role for the secreted glycoprotein Dickkopf 3 (Dkk3) in sarcopenia. Forced expression of Dkk3 in muscles in young mi...

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Detalles Bibliográficos
Autores principales:	Yin, Jie, Yang, Lele, Xie, Yangli, Liu, Yan, Li, Sheng, Yang, Wenjun, Xu, Bo, Ji, Hongbin, Ding, Lianghua, Wang, Kun, Li, Gang, Chen, Lin, Hu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931527/ https://www.ncbi.nlm.nih.gov/pubmed/29717119 http://dx.doi.org/10.1038/s41467-018-04038-6

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