Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Leprosy, a chronic infectious disease caused by Mycobacterium leprae (M. leprae), was very common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval skeletons from Denmark that show lesions specific for lepromatous leprosy (LL). First, we test the remains for M. lepra...

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Detalles Bibliográficos
Autores principales: Krause-Kyora, Ben, Nutsua, Marcel, Boehme, Lisa, Pierini, Federica, Pedersen, Dorthe Dangvard, Kornell, Sabin-Christin, Drichel, Dmitriy, Bonazzi, Marion, Möbus, Lena, Tarp, Peter, Susat, Julian, Bosse, Esther, Willburger, Beatrix, Schmidt, Alexander H., Sauter, Jürgen, Franke, Andre, Wittig, Michael, Caliebe, Amke, Nothnagel, Michael, Schreiber, Stefan, Boldsen, Jesper L., Lenz, Tobias L., Nebel, Almut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931558/
https://www.ncbi.nlm.nih.gov/pubmed/29717136
http://dx.doi.org/10.1038/s41467-018-03857-x

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