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Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification
Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ. Here, we describe the construction of iEC2812, a genome scale metabolic reconstructi...
Autores principales: | McGarrity, Sarah, Anuforo, Ósk, Halldórsson, Haraldur, Bergmann, Andreas, Halldórsson, Skarphéðinn, Palsson, Sirus, Henriksen, Hanne H., Johansson, Pär Ingemar, Rolfsson, Óttar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931560/ https://www.ncbi.nlm.nih.gov/pubmed/29717213 http://dx.doi.org/10.1038/s41598-018-25015-5 |
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