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Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ. Here, we describe the construction of iEC2812, a genome scale metabolic reconstructi...

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Detalles Bibliográficos
Autores principales: McGarrity, Sarah, Anuforo, Ósk, Halldórsson, Haraldur, Bergmann, Andreas, Halldórsson, Skarphéðinn, Palsson, Sirus, Henriksen, Hanne H., Johansson, Pär Ingemar, Rolfsson, Óttar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931560/
https://www.ncbi.nlm.nih.gov/pubmed/29717213
http://dx.doi.org/10.1038/s41598-018-25015-5

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