Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes

TLR sensing of pathogens triggers monocyte activation to initiate the host innate immune response to infection. Monocytes can dynamically adapt to different TLR agonists inducing different patterns of inflammatory response, and the sequence of exposure to TLRs can dramatically modulate cell activati...

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Detalles Bibliográficos
Autores principales: Monguió-Tortajada, Marta, Franquesa, Marcella, Sarrias, Maria-Rosa, Borràs, Francesc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931601/
https://www.ncbi.nlm.nih.gov/pubmed/29717111
http://dx.doi.org/10.1038/s41419-018-0520-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931601/
https://www.ncbi.nlm.nih.gov/pubmed/29717111
http://dx.doi.org/10.1038/s41419-018-0520-2

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