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Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes
TLR sensing of pathogens triggers monocyte activation to initiate the host innate immune response to infection. Monocytes can dynamically adapt to different TLR agonists inducing different patterns of inflammatory response, and the sequence of exposure to TLRs can dramatically modulate cell activati...
Autores principales: | Monguió-Tortajada, Marta, Franquesa, Marcella, Sarrias, Maria-Rosa, Borràs, Francesc E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931601/ https://www.ncbi.nlm.nih.gov/pubmed/29717111 http://dx.doi.org/10.1038/s41419-018-0520-2 |
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