Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses

Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses (SIVs) have become predominant in pig populations in China and have recently been reported to have the most potential to raise the next pandemic in humans. The mutation D701N in the PB2 protein, which accounts for 31% of H1N1 SIVs, has previ...

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Detalles Bibliográficos
Autores principales: Liu, Suli, Zhu, Wenfei, Feng, Zhaomin, Gao, Rongbao, Guo, Junfeng, Li, Xiyan, Liu, Jia, Wang, Dayan, Shu, Yuelong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931605/
https://www.ncbi.nlm.nih.gov/pubmed/29717109
http://dx.doi.org/10.1038/s41426-018-0073-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931605/
https://www.ncbi.nlm.nih.gov/pubmed/29717109
http://dx.doi.org/10.1038/s41426-018-0073-6

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