Morphophysiological changes in the splenic extracellular matrix of Leishmania infantum-naturally infected dogs is associated with alterations in lymphoid niches and the CD4+ T cell frequency in spleens

The spleen is one of the main affected organs in canine visceral leishmaniasis (CVL). Disorganization of the splenic white pulp (SWP) has been associated with immunosuppression and disease progression. This study aims to assess structural and cellular changes in the splenic extracellular matrix of d...

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Detalles Bibliográficos
Autores principales: da Silva, Aurea Virginia Andrade, Figueiredo, Fabiano Borges, Menezes, Rodrigo Caldas, Mendes-Junior, Arthur Augusto, de Miranda, Luisa Helena Monteiro, Cupolillo, Elisa, Porrozzi, Renato, Morgado, Fernanda Nazaré
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931683/
https://www.ncbi.nlm.nih.gov/pubmed/29677186
http://dx.doi.org/10.1371/journal.pntd.0006445

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