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Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria

BACKGROUND: The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients with <30% and <70% of normal G6PD activity a...

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Detalles Bibliográficos
Autores principales:	Watson, James, Taylor, Walter R. J., Bancone, Germana, Chu, Cindy S., Jittamala, Podjanee, White, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931686/ https://www.ncbi.nlm.nih.gov/pubmed/29677199 http://dx.doi.org/10.1371/journal.pntd.0006440

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