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The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in Caenorhabditis elegans

UBR1 is an E3 ubiquitin ligase best known for its ability to target protein degradation by the N-end rule. The physiological functions of UBR family proteins, however, remain not fully understood. We found that the functional loss of C. elegans UBR-1 leads to a specific motor deficit: when adult ani...

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Detalles Bibliográficos
Autores principales:	Chitturi, Jyothsna, Hung, Wesley, Rahman, Anas M. Abdel, Wu, Min, Lim, Maria A., Calarco, John, Baran, Renee, Huang, Xun, Dennis, James W., Zhen, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931689/ https://www.ncbi.nlm.nih.gov/pubmed/29649217 http://dx.doi.org/10.1371/journal.pgen.1007303

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