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SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties
BACKGROUND: Serine proteases are important virulence factors for many pathogens. Recently, we discovered a group of trypsin-like serine proteases with domain organization unique to flatworm parasites and containing a thrombospondin type 1 repeat (TSR-1). These proteases are recognized as antigens du...
Autores principales: | Leontovyč, Adrian, Ulrychová, Lenka, O’Donoghue, Anthony J., Vondrášek, Jiří, Marešová, Lucie, Hubálek, Martin, Fajtová, Pavla, Chanová, Marta, Jiang, Zhenze, Craik, Charles S., Caffrey, Conor R., Mareš, Michael, Dvořák, Jan, Horn, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931690/ https://www.ncbi.nlm.nih.gov/pubmed/29677188 http://dx.doi.org/10.1371/journal.pntd.0006446 |
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