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Inherent flexibility of CLIC6 revealed by crystallographic and solution studies
Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membranes and mediate ion conduction in vitro, suggesting multim...
Autores principales: | Ferofontov, Alisa, Strulovich, Roi, Marom, Milit, Giladi, Moshe, Haitin, Yoni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931990/ https://www.ncbi.nlm.nih.gov/pubmed/29720717 http://dx.doi.org/10.1038/s41598-018-25231-z |
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