Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite

There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable...

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Detalles Bibliográficos
Autores principales: Wei, Zheng, Wang, Yanchun, Zhang, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931993/
https://www.ncbi.nlm.nih.gov/pubmed/29720604
http://dx.doi.org/10.1038/s41598-018-25196-z
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author Wei, Zheng
Wang, Yanchun
Zhang, Junping
author_facet Wei, Zheng
Wang, Yanchun
Zhang, Junping
author_sort Wei, Zheng
collection PubMed
description There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM.
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spelling pubmed-59319932018-08-29 Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite Wei, Zheng Wang, Yanchun Zhang, Junping Sci Rep Article There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM. Nature Publishing Group UK 2018-05-02 /pmc/articles/PMC5931993/ /pubmed/29720604 http://dx.doi.org/10.1038/s41598-018-25196-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wei, Zheng
Wang, Yanchun
Zhang, Junping
Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_full Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_fullStr Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_full_unstemmed Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_short Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
title_sort electrochemical detection of ngf using a reduced graphene oxide- titanium nitride nanocomposite
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931993/
https://www.ncbi.nlm.nih.gov/pubmed/29720604
http://dx.doi.org/10.1038/s41598-018-25196-z
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AT wangyanchun electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite
AT zhangjunping electrochemicaldetectionofngfusingareducedgrapheneoxidetitaniumnitridenanocomposite

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