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A proteomic analysis of an in vitro knock-out of miR-200c

Loss of miR-200c is correlated to advanced cancer-subtypes due to increased EMT and decreased treatment efficacy by chemotherapeutics. As miRNAs regulate a multitude of targets, the analysis of differentially expressed proteins upon a genomic knock-out (KO) is of interest. In this study, we generate...

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Detalles Bibliográficos
Autores principales: Ljepoja, Bojan, García-Roman, Jonathan, Sommer, Ann-Katrin, Fröhlich, Thomas, Arnold, Georg J., Wagner, Ernst, Roidl, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931999/
https://www.ncbi.nlm.nih.gov/pubmed/29720730
http://dx.doi.org/10.1038/s41598-018-25240-y