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Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments

Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accomp...

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Autores principales: Wang, Biao, Kong, Lingbo, Zhu, Ziqi, Gao, Wenjie, Guo, Hua, Wang, Xiaodong, Li, Hui, Zhao, Qinpeng, Zhang, Haiping, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932000/
https://www.ncbi.nlm.nih.gov/pubmed/29720686
http://dx.doi.org/10.1038/s41598-018-25142-z
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author Wang, Biao
Kong, Lingbo
Zhu, Ziqi
Gao, Wenjie
Guo, Hua
Wang, Xiaodong
Li, Hui
Zhao, Qinpeng
Zhang, Haiping
Hao, Dingjun
author_facet Wang, Biao
Kong, Lingbo
Zhu, Ziqi
Gao, Wenjie
Guo, Hua
Wang, Xiaodong
Li, Hui
Zhao, Qinpeng
Zhang, Haiping
Hao, Dingjun
author_sort Wang, Biao
collection PubMed
description Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accompanied by sinus tract formation. In this study, 21 recurrent patients out of 87 patients with complex spinal tuberculosis were reviewed. The data of the patients, including age, gender, existence of drug-resistant mycobacterium tuberculosis, postoperative standard chemotherapy, completeness of lesion debridement, reconstruction of the spinal stability, nutritional status, accompaniment by tuberculosis in other regions, timing of the operations, and areas of the lesions, were collected for single- and multiple-factor analyses. The clinical outcomes were evaluated by long-term follow-ups. The results showed that 7 factors were significantly associated with postoperative recurrence of complex spinal tuberculosis accompanied by sinus tract formation. This suggested that when we treat complex spinal tuberculosis, we should pay more attention to these seven indicators to avoid postoperative recurrence, and our clinical outcomes suggested that it is difficult to treat recurrent complicated spinal tuberculosis combined with sinus tract formation. The key for successful surgical treatment includes effective chemotherapy, radical debridement and proper reconstruction of spinal stability.
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spelling pubmed-59320002018-08-29 Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments Wang, Biao Kong, Lingbo Zhu, Ziqi Gao, Wenjie Guo, Hua Wang, Xiaodong Li, Hui Zhao, Qinpeng Zhang, Haiping Hao, Dingjun Sci Rep Article Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accompanied by sinus tract formation. In this study, 21 recurrent patients out of 87 patients with complex spinal tuberculosis were reviewed. The data of the patients, including age, gender, existence of drug-resistant mycobacterium tuberculosis, postoperative standard chemotherapy, completeness of lesion debridement, reconstruction of the spinal stability, nutritional status, accompaniment by tuberculosis in other regions, timing of the operations, and areas of the lesions, were collected for single- and multiple-factor analyses. The clinical outcomes were evaluated by long-term follow-ups. The results showed that 7 factors were significantly associated with postoperative recurrence of complex spinal tuberculosis accompanied by sinus tract formation. This suggested that when we treat complex spinal tuberculosis, we should pay more attention to these seven indicators to avoid postoperative recurrence, and our clinical outcomes suggested that it is difficult to treat recurrent complicated spinal tuberculosis combined with sinus tract formation. The key for successful surgical treatment includes effective chemotherapy, radical debridement and proper reconstruction of spinal stability. Nature Publishing Group UK 2018-05-02 /pmc/articles/PMC5932000/ /pubmed/29720686 http://dx.doi.org/10.1038/s41598-018-25142-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wang, Biao
Kong, Lingbo
Zhu, Ziqi
Gao, Wenjie
Guo, Hua
Wang, Xiaodong
Li, Hui
Zhao, Qinpeng
Zhang, Haiping
Hao, Dingjun
Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_full Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_fullStr Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_full_unstemmed Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_short Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_sort recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932000/
https://www.ncbi.nlm.nih.gov/pubmed/29720686
http://dx.doi.org/10.1038/s41598-018-25142-z
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