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Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism

Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear. αKlotho, a putative enzyme possessing β-glucuronidase activity and also a permissive co-receptor for FGF23 to bind...

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Detalles Bibliográficos
Autores principales:	Takeshita, Ai, Kawakami, Kazuki, Furushima, Kenryo, Miyajima, Masayasu, Sakaguchi, Kazushige
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932018/ https://www.ncbi.nlm.nih.gov/pubmed/29720668 http://dx.doi.org/10.1038/s41598-018-25087-3

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