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P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development
Ensuring the fitness of the pluripotent cells that will contribute to future development is important both for the integrity of the germline and for proper embryogenesis. Consequently, it is becoming increasingly apparent that pluripotent cells can compare their fitness levels and signal the elimina...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932021/ https://www.ncbi.nlm.nih.gov/pubmed/29720666 http://dx.doi.org/10.1038/s41467-018-04167-y |