P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development

Ensuring the fitness of the pluripotent cells that will contribute to future development is important both for the integrity of the germline and for proper embryogenesis. Consequently, it is becoming increasingly apparent that pluripotent cells can compare their fitness levels and signal the elimina...

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Detalles Bibliográficos
Autores principales: Bowling, Sarah, Di Gregorio, Aida, Sancho, Margarida, Pozzi, Sara, Aarts, Marieke, Signore, Massimo, D. Schneider, Michael, Martinez-Barbera, Juan Pedro, Gil, Jesús, Rodríguez, Tristan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932021/
https://www.ncbi.nlm.nih.gov/pubmed/29720666
http://dx.doi.org/10.1038/s41467-018-04167-y

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