Aspirin: the miracle drug?

Aspirin use is associated with reduction of esophageal adenocarcinoma but it is not known if it does so by preventing the development of Barrett’s esophagus or by reducing neoplastic progression in patients with Barrett’s esophagus. There is sparse literature to support the former assumption especia...

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Autor principal: Thota, Prashanthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932067/
https://www.ncbi.nlm.nih.gov/pubmed/29720629
http://dx.doi.org/10.1038/s41424-018-0009-4
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author Thota, Prashanthi N.
author_facet Thota, Prashanthi N.
author_sort Thota, Prashanthi N.
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description Aspirin use is associated with reduction of esophageal adenocarcinoma but it is not known if it does so by preventing the development of Barrett’s esophagus or by reducing neoplastic progression in patients with Barrett’s esophagus. There is sparse literature to support the former assumption especially in women. This study by Jovani et al. based on Nurses’ Health Study reports 27% lower risk of Barrett’s esophagus among women using aspirin. The protective effect seems to increase with higher frequency and longer duration of aspirin use. This study provides evidence for lower prevalence of Barrett’s esophagus in female aspirin users.
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spelling pubmed-59320672018-05-04 Aspirin: the miracle drug? Thota, Prashanthi N. Clin Transl Gastroenterol Editorial Aspirin use is associated with reduction of esophageal adenocarcinoma but it is not known if it does so by preventing the development of Barrett’s esophagus or by reducing neoplastic progression in patients with Barrett’s esophagus. There is sparse literature to support the former assumption especially in women. This study by Jovani et al. based on Nurses’ Health Study reports 27% lower risk of Barrett’s esophagus among women using aspirin. The protective effect seems to increase with higher frequency and longer duration of aspirin use. This study provides evidence for lower prevalence of Barrett’s esophagus in female aspirin users. Nature Publishing Group US 2018-05-02 /pmc/articles/PMC5932067/ /pubmed/29720629 http://dx.doi.org/10.1038/s41424-018-0009-4 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, and provide a link to the Creative Commons license. You do not have permission under this license to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, http://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Editorial
Thota, Prashanthi N.
Aspirin: the miracle drug?
title Aspirin: the miracle drug?
title_full Aspirin: the miracle drug?
title_fullStr Aspirin: the miracle drug?
title_full_unstemmed Aspirin: the miracle drug?
title_short Aspirin: the miracle drug?
title_sort aspirin: the miracle drug?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932067/
https://www.ncbi.nlm.nih.gov/pubmed/29720629
http://dx.doi.org/10.1038/s41424-018-0009-4
work_keys_str_mv AT thotaprashanthin aspirinthemiracledrug

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