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Mitochondrial 10398A>G NADH-Dehydrogenase Subunit 3 of Complex I Is Frequently Altered in Intra-Axial Brain Tumors in Malaysia

BACKGROUND: Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA damage and lead to carcinogenesis. The mitochondrial 10398A>G alteration in NADH-dehydrogenase subunit 3 (ND3) can severely impair complex I, a key component of ROS p...

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Detalles Bibliográficos
Autores principales:	Mohamed Yusoff, Abdul Aziz, Zulfakhar, Fatin Najwa, Mohd Khair, Siti Zulaikha Nashwa, Wan Abdullah, Wan Salihah, Abdullah, Jafri Malin, Idris, Zamzuri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932297/ https://www.ncbi.nlm.nih.gov/pubmed/29717568 http://dx.doi.org/10.14791/btrt.2018.6.e5

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