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The Transcription Factor Hif-1 Enhances the Radio-Resistance of Mouse MSCs

Mesenchymal stromal cells (MSCs) are multipotent progenitors supporting bone marrow hematopoiesis. MSCs have an efficient DNA damage response (DDR) and are consequently relatively radio-resistant cells. Therefore, MSCs are key to hematopoietic reconstitution following total body irradiation (TBI) an...

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Detalles Bibliográficos
Autores principales:	Calvo-Asensio, Irene, Dillon, Eugène T., Lowndes, Noel F., Ceredig, Rhodri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932323/ https://www.ncbi.nlm.nih.gov/pubmed/29755367 http://dx.doi.org/10.3389/fphys.2018.00439

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