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The Role of Optineurin in Antiviral Type I Interferon Production

After a viral infection and the stimulation of some pattern-recognition receptors as the toll-like receptor 3 in the endosomes or the RIG-I-like receptors in the cytosol, activation of the IKK-related kinase TBK1 leads to the production of type I interferons (IFNs) after phosphorylation of the trans...

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Detalles Bibliográficos
Autores principales: Outlioua, Ahmed, Pourcelot, Marie, Arnoult, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932347/
https://www.ncbi.nlm.nih.gov/pubmed/29755463
http://dx.doi.org/10.3389/fimmu.2018.00853

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