Cargando…

Analogous β-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice

The analogous β-carboline alkaloids, harmaline (HAL) and harmine (HAR), possess a variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity, antioxidant, anti-inflammatory, and many others, and have great potential for treating Alzheimer’s disease (AD). However, stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shu-Ping, Wang, Yu-Wen, Qi, Sheng-Lan, Zhang, Yun-Peng, Deng, Gang, Ding, Wen-Zheng, Ma, Chao, Lin, Qi-Yan, Guan, Hui-Da, Liu, Wei, Cheng, Xue-Mei, Wang, Chang-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932362/ https://www.ncbi.nlm.nih.gov/pubmed/29755345 http://dx.doi.org/10.3389/fphar.2018.00346

Ejemplares similares

Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2
por: Li, Shuping, et al.
Publicado: (2017)

Innovative spectrofluorometric method for determination of harmaline and harmine in different matrices
por: Abdelazim, Ahmed H., et al.
Publicado: (2023)

Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact
por: Brito-da-Costa, Andreia Machado, et al.
Publicado: (2020)

Exploring the Structural Importance of the C3=C4 Double Bond in Plant Alkaloids Harmine and Harmaline on Their Binding Interactions with Hemoglobin
por: Burman, Mangal Deep, et al.
Publicado: (2023)

Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States
por: Cao, Ning, et al.
Publicado: (2022)

Synthesis and Antibacterial Study of Novel Harmine Derivatives and Tetrahydro-β-Carboline Derivatives In Vitro
por: Liang, Yan, et al.
Publicado: (2022)

Kai Xin San ameliorates scopolamine-induced cognitive dysfunction
por: Xu, Yu-Min, et al.
Publicado: (2019)

Riluzole Ameliorates Harmaline-induced Tremor in Rat
por: Shourmasti, Fatemeh Rahimi, et al.
Publicado: (2014)

Harmine and Harmaline Downregulate TCDD-Induced Cyp1a1 in the Livers and Lungs of C57BL/6 Mice
por: El Gendy, Mohamed A. M., et al.
Publicado: (2013)

The β-carboline Harmine Induces Actin Dynamic Remodeling and Abrogates the Malignant Phenotype in Tumorigenic Cells
por: Le Moigne, Ronan, et al.
Publicado: (2020)

Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling
por: Lu, Cong, et al.
Publicado: (2018)

The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype
por: Zhao, Lei, et al.
Publicado: (2013)

Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes
por: Dibwe, Dya Fita, et al.
Publicado: (2022)

Recent Advances in the Synthesis of β-Carboline Alkaloids
por: Szabó, Tímea, et al.
Publicado: (2021)

Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesis
por: Carvalho, Annelise, et al.
Publicado: (2017)

Harmine Ameliorates Cognitive Impairment by Inhibiting NLRP3 Inflammasome Activation and Enhancing the BDNF/TrkB Signaling Pathway in STZ-Induced Diabetic Rats
por: Liu, Peifang, et al.
Publicado: (2020)

β-Carboline Compounds, Including Harmine, Inhibit DYRK1A and Tau Phosphorylation at Multiple Alzheimer's Disease-Related Sites
por: Frost, Danielle, et al.
Publicado: (2011)

Inhibition of Acetylcholinesterase and Amyloid-β Aggregation by Piceatannol and Analogs: Assessing In Vitro and In Vivo Impact on a Murine Model of Scopolamine-Induced Memory Impairment
por: Sie, Yi-Yan, et al.
Publicado: (2023)

Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats
por: Lee, Bombi, et al.
Publicado: (2012)

Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives
por: Li, Zhibin, et al.
Publicado: (2015)

Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress
por: Al-Amin, Md. Yusuf, et al.
Publicado: (2022)

The β-carboline Harmine improves the therapeutic benefit of anti-PD1 in melanoma by increasing the MHC-I-dependent antigen presentation
por: Noman, Muhammad Zaeem, et al.
Publicado: (2022)

Novel insights on acetylcholinesterase inhibition by Convolvuluspluricaulis, scopolamine and their combination in zebrafish
por: Karunakaran, Kalyani Bindu, et al.
Publicado: (2022)

Amelioration of Cognitive Deficit by Embelin in a Scopolamine-Induced Alzheimer’s Disease-Like Condition in a Rat Model
por: Bhuvanendran, Saatheeyavaane, et al.
Publicado: (2018)

β-carboline alkaloids from Trigonostemon filipes and Trigonostemon lii
por: Li, Shi-Fei, et al.
Publicado: (2012)

Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer’s disease
por: Du, Hongtao, et al.
Publicado: (2023)

Lavandula stoechas (L) a Very Potent Antioxidant Attenuates Dementia in Scopolamine Induced Memory Deficit Mice
por: Mushtaq, Aamir, et al.
Publicado: (2018)

In vitro Effect of Harmine Alkaloid and Its N-Methyl Derivatives Against Toxoplasma gondii
por: Alomar, Maria L., et al.
Publicado: (2021)

Scopolamine-induced “cholinergic stress test” in the elderly
por: Román, Gustavo C., et al.
Publicado: (2014)

In vitro evaluation of β-carboline alkaloids as potential anti-Toxoplasma agents
por: Alomar, Maria L, et al.
Publicado: (2013)

β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO)
por: Herraiz, Tomás
Publicado: (2023)

Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs
por: Hussain, Haya, et al.
Publicado: (2022)

Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy
por: Qin, Jiang-Jiang, et al.
Publicado: (2018)

Apigenin Ameliorates Scopolamine-Induced Cognitive Dysfunction and Neuronal Damage in Mice
por: Kim, Yeojin, et al.
Publicado: (2021)

Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis
por: Ren, Chao, et al.
Publicado: (2021)

The effect of transdermal scopolamine for the prevention of postoperative nausea and vomiting
por: Antor, María A., et al.
Publicado: (2014)

Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca
por: Berlowitz, Ilana, et al.
Publicado: (2022)

Simplification of Natural β-Carboline Alkaloids to Obtain Indole Derivatives as Potent Fungicides against Rice Sheath Blight
por: Zeng, Jie, et al.
Publicado: (2020)

Isoquinoline Alkaloids and Indole Alkaloids Attenuate Aortic Atherosclerosis in Apolipoprotein E Deficient Mice: A Systematic Review and Meta-Analysis
por: Zhang, Yibing, et al.
Publicado: (2018)

Anti-adipogenic Effect of β-Carboline Alkaloids from Garlic (Allium sativum)
por: Baek, Su Cheol, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ado7nad2ctiacqeq3ilbq9llv9