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Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells
Proteinase 3 (PR3) is the autoantigen in granulomatosis with polyangiitis, an autoimmune necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Moreover, PR3 is a serine protease whose membrane expression can potentiate inflammatory diseases such as ANCA-associated va...
Autores principales: | Tacnet-Delorme, Pascale, Gabillet, Julie, Chatfield, Simon, Thieblemont, Nathalie, Frachet, Philippe, Witko-Sarsat, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932363/ https://www.ncbi.nlm.nih.gov/pubmed/29755460 http://dx.doi.org/10.3389/fimmu.2018.00818 |
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