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Targeting Regulatory T Cells to Treat Patients With Systemic Lupus Erythematosus
Regulatory T cells (Tregs) are central in integration and maintenance of immune homeostasis. Since breakdown of self-tolerance is a major culprit in the pathogenesis of systemic lupus erythematosus (SLE), restoration of the immune tolerance through the manipulation of Tregs can be exploited to treat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932391/ https://www.ncbi.nlm.nih.gov/pubmed/29755456 http://dx.doi.org/10.3389/fimmu.2018.00786 |