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Detection and Structural Characterization of Nucleophiles Trapped Reactive Metabolites of Limonin Using Liquid Chromatography-Mass Spectrometry

Limonin (LIM), a furan-containing limonoid, is one of the most abundant components of Dictamnus dasycarpus Turcz. Recent studies demonstrated that LIM has great potential for inhibiting the activity of drug-metabolizing enzymes. However, the mechanisms of LIM-induced enzyme inactivation processes re...

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Detalles Bibliográficos
Autores principales:	Deng, Yujie, Fu, Yudong, Xu, Shumin, Wang, Ping, Yang, Nailong, Li, Chengqian, Yu, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932435/ https://www.ncbi.nlm.nih.gov/pubmed/29850372 http://dx.doi.org/10.1155/2018/3797389

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