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Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, Controlled Trial

BACKGROUNDS: Stroke is the leading cause of death and long-term disability. Oxidative stress is elevated during occurrence of acute ischemic stroke (AIS). Soluble LOX-1 (sLOX-1) and NO are used as biomarkers for vascular oxidative stress that can reflect stabilization of atherosclerotic plaque. Prev...

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Detalles Bibliográficos
Autores principales: Uransilp, Nattaphol, Chaiyawatthanananthn, Pannawat, Muengtaweepongsa, Sombat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932464/
https://www.ncbi.nlm.nih.gov/pubmed/29850244
http://dx.doi.org/10.1155/2018/7268924