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Knockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling Pathway

Preeclampsia is a pregnancy-related disease with increasing maternal and perinatal morbidity and mortality worldwide. Defective trophoblast invasion is considered to be a major factor in the pathophysiological mechanism of preeclampsia. Heparanase, the only endo-β-glucuronidase in mammalian cells, h...

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Detalles Bibliográficos
Autores principales:	Che, Guanglu, Wang, Yanyun, Zhou, Bin, Gao, Linbo, Wang, Tao, Yuan, Fang, Zhang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932509/ https://www.ncbi.nlm.nih.gov/pubmed/29849826 http://dx.doi.org/10.1155/2018/7413027

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