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Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors

The INK4/ARF locus at chromosome 9p21 encoding p14(ARF), p15(INK4B) and p16(INK4A) is a major tumor suppressor locus, constituting an important barrier for tumor growth. It is frequently inactivated in cancers, especially in urothelial carcinoma (UC). In addition to deletions and DNA hypermethylatio...

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Detalles Bibliográficos
Autores principales:	Hoffmann, Michèle J., Dehn, Judith, Droop, Johanna, Niegisch, Günter, Niedworok, Christian, Szarvas, Tibor, Schulz, Wolfgang A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932551/ https://www.ncbi.nlm.nih.gov/pubmed/29861427 http://dx.doi.org/10.3390/ncrna1030266

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