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LXRɑ participates in the mTOR/S6K1/SREBP-1c signaling pathway during sodium palmitate-induced lipogenesis in HepG2 cells

BACKGROUND: The aim of this study was to investigate how the signaling pathway downstream of mTOR/S6K1 contributes to the regulation of SREBP-1c expression during lipogenesis in HepG2 cells. METHODS: The model of steatosis was established using human hepatocytes HepG2 and inducting them with sodium...

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Detalles Bibliográficos
Autores principales: Zhou, Youping, Yu, Shengjie, Cai, Can, Zhong, Li, Yu, Huihong, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932778/
https://www.ncbi.nlm.nih.gov/pubmed/29743930
http://dx.doi.org/10.1186/s12986-018-0268-9