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Inflammation functions as a key mediator in the link between ACPA and erosion development: an association study in Clinically Suspect Arthralgia

BACKGROUND: Anti-citrullinated protein antibodies (ACPA) are associated with more severe joint erosions in rheumatoid arthritis (RA), but the underlying mechanism is unclear. Recent in vitro and murine studies indicate that ACPAs can directly activate osteoclasts leading to bone erosions and pain. T...

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Detalles Bibliográficos
Autores principales:	ten Brinck, R. M., Toes, R. E. M., van der Helm–van Mil, A. H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932781/ https://www.ncbi.nlm.nih.gov/pubmed/29720256 http://dx.doi.org/10.1186/s13075-018-1574-3

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