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Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration

BACKGROUND: Second generation antipsychotics (SGAs) induce glucometabolic side-effects, such as hyperglycemia and insulin resistance, which pose a therapeutic challenge for mental illness. Sphingolipids play a role in glycaemic balance and insulin resistance. Endoplasmic reticulum (ER) stress contri...

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Detalles Bibliográficos
Autores principales:	Weston-Green, Katrina, Babic, Ilijana, de Santis, Michael, Pan, Bo, Montgomery, Magdalene K., Mitchell, Todd, Huang, Xu-Feng, Nealon, Jessica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932814/ https://www.ncbi.nlm.nih.gov/pubmed/29720183 http://dx.doi.org/10.1186/s12929-018-0437-1

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