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Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
BACKGROUND: Ischemic stroke induced matrixmetallo-proteinase-9 (MMP-9) upregulation, which increased blood-brain barrier permeability. Studies demonstrated that mesenchymal stem cell therapy protected blood-brain barrier disruption from several cerebrovascular diseases. However, the underlying mecha...
Autores principales: | Cheng, Zhuo, Wang, Liping, Qu, Meijie, Liang, Huaibin, Li, Wanlu, Li, Yongfang, Deng, Lidong, Zhang, Zhijun, Yang, Guo-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932816/ https://www.ncbi.nlm.nih.gov/pubmed/29724240 http://dx.doi.org/10.1186/s12974-018-1153-1 |
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