Cargando…

Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation

BACKGROUND: Autologous chondrocyte implantation (ACI) has a failure rate of approximately 20%, but it is yet to be fully understood why. Biomarkers are needed that can pre-operatively predict in which patients it is likely to fail, so that alternative or individualised therapies can be offered. We p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hulme, Charlotte H., Wilson, Emma L., Fuller, Heidi R., Roberts, Sally, Richardson, James B., Gallacher, Pete, Peffers, Mandy J., Shirran, Sally L., Botting, Catherine H., Wright, Karina T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932832/ https://www.ncbi.nlm.nih.gov/pubmed/29720234 http://dx.doi.org/10.1186/s13075-018-1573-4

Ejemplares similares

Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles
por: Hulme, Charlotte H., et al.
Publicado: (2017)

Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening
por: Hulme, Charlotte H., et al.
Publicado: (2023)

Investigation of the blood proteome in response to spinal cord injury in rodent models
por: Hulme, Charlotte H., et al.
Publicado: (2021)

The synovial fluid proteome differentiates between septic and nonseptic articular pathologies
por: Anderson, James R., et al.
Publicado: (2019)

Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies
por: Brown, Sharon J., et al.
Publicado: (2017)

Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics
por: Anderson, James R., et al.
Publicado: (2020)

A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods
por: Shirran, Sally L., et al.
Publicado: (2010)

Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells: A SWATH-MS study
por: Arya, Swati, et al.
Publicado: (2019)

The synovial fluid from patients with focal cartilage defects contains mesenchymal stem/stromal cells and macrophages with pro- and anti-inflammatory phenotypes
por: Garcia, John, et al.
Publicado: (2020)

Increased Production of Clusterin in Biopsies of Repair Tissue following Autologous Chondrocyte Implantation
por: McCarthy, Helen S., et al.
Publicado: (2013)

Lubricin: Its Presence in Repair Cartilage following Treatment with Autologous Chondrocyte Implantation
por: Roberts, Sally, et al.
Publicado: (2010)

Development of a Tool to Predict Outcome of Autologous Chondrocyte Implantation
por: Dugard, M. Naomi, et al.
Publicado: (2016)

Synovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: Proteomics analysis of porcine knee synovial fluid
por: Kiapour, Ata M., et al.
Publicado: (2019)

Synovial fluid proteome in rheumatoid arthritis
por: Bhattacharjee, Mitali, et al.
Publicado: (2016)

Characterization of the porcine synovial fluid proteome and a comparison to the plasma proteome
por: Bennike, Tue Bjerg, et al.
Publicado: (2015)

The Upscale Manufacture of Chondrocytes for Allogeneic Cartilage Therapies
por: Hulme, Charlotte H., et al.
Publicado: (2023)

Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development
por: Fuller, Heidi R., et al.
Publicado: (2016)

Proteomic analysis of human osteoarthritis synovial fluid
por: Balakrishnan, Lavanya, et al.
Publicado: (2014)

The Proteome Signatures of Fibroblasts from Patients with Severe, Intermediate and Mild Spinal Muscular Atrophy Show Limited Overlap
por: Brown, Sharon J., et al.
Publicado: (2022)

Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus
por: Garcia, John, et al.
Publicado: (2016)

Glycosaminoglycan profiles of repair tissue formed following autologous chondrocyte implantation differ from control cartilage
por: Sharma, Aarti, et al.
Publicado: (2007)

Chopping off the chondrocyte proteome
por: Dvir-Ginzberg, Mona, et al.
Publicado: (2015)

Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology
por: Roberts, Sally, et al.
Publicado: (2003)

Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases
por: Wang, Jingsong, et al.
Publicado: (2019)

Changes in the synovial cell proteome induced by hypoxia
por: El-Gabalawy, H, et al.
Publicado: (2003)

Neopeptide Analyser: A software tool for neopeptide discovery in proteomics data
por: Peffers, Mandy, et al.
Publicado: (2017)

Towards Precision Medicine for Osteoarthritis: Focus on the Synovial Fluid Proteome
por: Moretti, Lorenzo, et al.
Publicado: (2022)

Biochemical and Proteomic Characterization of Alkaptonuric Chondrocytes
por: Braconi, Daniela, et al.
Publicado: (2012)

Proteome Alterations in Equine Osteochondrotic Chondrocytes
por: Chiaradia, Elisabetta, et al.
Publicado: (2019)

Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies
por: Anderson, James R., et al.
Publicado: (2018)

Evaluating Joint Morbidity after Chondral Harvest for Autologous Chondrocyte Implantation (ACI): A Study of ACI-Treated Ankles and Hips with a Knee Chondral Harvest
por: McCarthy, Helen S., et al.
Publicado: (2016)

Proteomic differences between native and tissue‐engineered tendon and ligament
por: Kharaz, Yalda A., et al.
Publicado: (2016)

Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat
por: Garcia, John, et al.
Publicado: (2016)

High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis
por: Gobezie, Reuben, et al.
Publicado: (2007)

Proteomic analysis of synovial fluid in osteoarthritis using SWATH-mass spectrometry
por: Liao, Weixiong, et al.
Publicado: (2018)

Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
por: Birkelund, Svend, et al.
Publicado: (2020)

Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
por: Muller, P. Robinson, et al.
Publicado: (2023)

Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in mice
por: Buschhart, Anna-Lena, et al.
Publicado: (2020)

Donor age affects proteome composition of tenocyte-derived engineered tendon
por: Turlo, Agnieszka J., et al.
Publicado: (2018)

Proteomic Analysis of Synovial Fibroblasts and Articular Chondrocytes Co-Cultures Reveals Valuable VIP-Modulated Inflammatory and Degradative Proteins in Osteoarthritis
por: Pérez-García, Selene, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ggv2ntj3g8ah24tfmgjq6ldsa7