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Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis

BACKGROUND: Osteoclast-mediated bone erosion is a central feature of rheumatoid arthritis (RA). Immune complexes, present in a large percentage of patients, bind to Fcγ receptors (FcγRs), thereby modulating the activity of immune cells. In this study, we investigated the contribution of FcγRs, and F...

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Detalles Bibliográficos
Autores principales: Di Ceglie, Irene, Ascone, Giuliana, Cremers, Niels A. J., Sloetjes, Annet W., Walgreen, Birgitte, Vogl, Thomas, Roth, Johannes, Verbeek, J. Sjef, van de Loo, Fons A. J., Koenders, Marije I., van der Kraan, Peter M., Blom, Arjen B., van den Bosch, Martijn H. J., van Lent, Peter L. E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932875/
https://www.ncbi.nlm.nih.gov/pubmed/29720243
http://dx.doi.org/10.1186/s13075-018-1584-1