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Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
BACKGROUND: Osteoclast-mediated bone erosion is a central feature of rheumatoid arthritis (RA). Immune complexes, present in a large percentage of patients, bind to Fcγ receptors (FcγRs), thereby modulating the activity of immune cells. In this study, we investigated the contribution of FcγRs, and F...
Autores principales: | Di Ceglie, Irene, Ascone, Giuliana, Cremers, Niels A. J., Sloetjes, Annet W., Walgreen, Birgitte, Vogl, Thomas, Roth, Johannes, Verbeek, J. Sjef, van de Loo, Fons A. J., Koenders, Marije I., van der Kraan, Peter M., Blom, Arjen B., van den Bosch, Martijn H. J., van Lent, Peter L. E. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932875/ https://www.ncbi.nlm.nih.gov/pubmed/29720243 http://dx.doi.org/10.1186/s13075-018-1584-1 |
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