Cargando…

Troxerutin Protects Kidney Tissue against BDE-47-Induced Inflammatory Damage through CXCR4-TXNIP/NLRP3 Signaling

2,2′,4,4′-Tetrabromodiphenyl ether (BDE-47) induces oxidative stress in kidney cells, but the underlying mechanism remains poorly understood. Troxerutin, a natural flavonoid, has potential antioxidant and anti-inflammatory efficacy. In this study, we assessed the effect of troxerutin on kidney damag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shan, Qun, Zheng, Gui-hong, Han, Xin-rui, Wen, Xin, Wang, Shan, Li, Meng-qiu, Zhuang, Juan, Zhang, Zi-Feng, Hu, Bin, Zhang, Yanqiu, Zheng, Yuan-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932985/ https://www.ncbi.nlm.nih.gov/pubmed/29849929 http://dx.doi.org/10.1155/2018/9865495

Ejemplares similares

Troxerutin Reduces Kidney Damage against BDE-47-Induced Apoptosis via Inhibiting NOX2 Activity and Increasing Nrf2 Activity
por: Shan, Qun, et al.
Publicado: (2017)

miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis
por: Pan, Zhiqiang, et al.
Publicado: (2018)

Placental transfer of the polybrominated diphenyl ethers BDE-47, BDE-99 and BDE-209 in a human placenta perfusion system: an experimental study
por: Frederiksen, Marie, et al.
Publicado: (2010)

Integrated Proteomic and Metabolomic Analysis of the Testes Characterizes BDE-47-Induced Reproductive Toxicity in Mice
por: Xu, Liang, et al.
Publicado: (2021)

Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures
por: Chen, Hao, et al.
Publicado: (2022)

Troxerutin Attenuates Enhancement of Hepatic Gluconeogenesis by Inhibiting NOD Activation-Mediated Inflammation in High-Fat Diet-Treated Mice
por: Zhang, Zifeng, et al.
Publicado: (2016)

Toxic effects of polybrominated diphenyl ethers (BDE 47 and 99) and localization of BDE-99–induced cyp1a mRNA in zebrafish larvae
por: Yang, Jie, et al.
Publicado: (2017)

BDE-47 Induces Mitochondrial Dysfunction and Endoplasmic Reticulum Stress to Inhibit Early Porcine Embryonic Development
por: Liu, Rong-Ping, et al.
Publicado: (2023)

Toxicity Effects of Combined Mixtures of BDE-47 and Nickel on the Microalgae Phaeodactylum tricornutum (Bacillariophyceae)
por: Shi, Xiaolai, et al.
Publicado: (2022)

Antiangiogenic Potential of Troxerutin and Chitosan Loaded Troxerutin on Chorioallantoic Membrane Model
por: Subbaraj, Gowtham Kumar, et al.
Publicado: (2023)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish
por: Chackal, Raphaël, et al.
Publicado: (2022)

Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis
por: Fu, Yan, et al.
Publicado: (2021)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
por: An, Xin, et al.
Publicado: (2020)

Mitteilungen des BDE
Publicado: (2020)

Mitteilungen des BDE
Publicado: (2020)

Mitteilungen des BDE
Publicado: (2021)

Mitteilungen des BDE
Publicado: (2021)

Mitteilungen des BDE
Publicado: (2021)

Mitteilungen des BDE
Publicado: (2022)

Mitteilungen des BDE
Publicado: (2021)

Mitteilungen des BDE
Publicado: (2021)

Mitteilungen des BDE
Publicado: (2022)

Mitteilungen des BDE
Publicado: (2022)

Hydroxylation Increases the Neurotoxic Potential of BDE-47 to Affect Exocytosis and Calcium Homeostasis in PC12 Cells
por: Dingemans, Milou M.L., et al.
Publicado: (2008)

High body burdens of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in California women.
por: Petreas, Myrto, et al.
Publicado: (2003)

Biotransformation of BDE-47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6
por: Feo, Maria Luisa, et al.
Publicado: (2012)

Transcriptional and Epigenetic Mechanisms Underlying Enhanced in Vitro Adipocyte Differentiation by the Brominated Flame Retardant BDE-47
por: Kamstra, Jorke H., et al.
Publicado: (2014)

BDE47 induces rat CYP3A1 by targeting the transcriptional regulation of miR-23b
por: Sun, Zhenzhen, et al.
Publicado: (2016)

Biocatalytic synthesis of acylated derivatives of troxerutin: their bioavailability and antioxidant properties in vitro
por: Xin, Xuan, et al.
Publicado: (2018)

Cerebral gene expression and neurobehavioural development after perinatal exposure to an environmentally relevant polybrominated diphenylether (BDE47)
por: Haave, Marte, et al.
Publicado: (2011)

Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency
por: McIntyre, Rebecca L, et al.
Publicado: (2015)

Uptake and biotransformation of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) in four marine microalgae species
por: Po, Beverly H. K., et al.
Publicado: (2017)

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction
por: Yang, Chun, et al.
Publicado: (2019)

The Regulatory Roles of MicroRNA in Effects of 2,2'4,4'-Tetrabromodiphenyl Ether (BDE47) on the Transcriptome of Zebrafish Larvae
por: Zhao, Jing, et al.
Publicado: (2017)

Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice
por: Zheng, Gui-Hong, et al.
Publicado: (2019)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

Chronic BDE-47 Exposure Aggravates Malignant Phenotypes and Chemoresistance by Activating ERK Through ERα and GPR30 in Endometrial Carcinoma
por: Zhang, Fan, et al.
Publicado: (2019)

Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways
por: Zhang, Hengshuai, et al.
Publicado: (2021)

Characterization of 2,2',4,4'-tetrabromodiphenyl ether (BDE47)-induced testicular toxicity via single-cell RNA-sequencing
por: Zhang, Wei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bs5gvei3b9sicnkuhg4oba0vhs