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The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study

Background: Benzodiazepines are driving-impairing medicines (DIM). This study presents current consumption of dispensed benzodiazepines in the Spanish general population, with a focus in pattern of use and concomitant medicines consumed with. Methods: A population-based registry study was carried ou...

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Autores principales: Herrera-Gómez, Francisco, Gutierrez-Abejón, Eduardo, Criado-Espegel, Paloma, Álvarez, F. Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933078/
https://www.ncbi.nlm.nih.gov/pubmed/29755352
http://dx.doi.org/10.3389/fphar.2018.00408
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author Herrera-Gómez, Francisco
Gutierrez-Abejón, Eduardo
Criado-Espegel, Paloma
Álvarez, F. Javier
author_facet Herrera-Gómez, Francisco
Gutierrez-Abejón, Eduardo
Criado-Espegel, Paloma
Álvarez, F. Javier
author_sort Herrera-Gómez, Francisco
collection PubMed
description Background: Benzodiazepines are driving-impairing medicines (DIM). This study presents current consumption of dispensed benzodiazepines in the Spanish general population, with a focus in pattern of use and concomitant medicines consumed with. Methods: A population-based registry study was carried out to assess the year-2016 granted benzodiazepines dispensation in Castile and León. Weighting was performed to obtain the adjusted benzodiazepine consumption for licensed drivers according to age and gender using our national drivers' license census data. Results: Benzodiazepines were used by 15.38% of the general population and 10.97% of drivers. Nearly 2% of the population and more than 1% of drivers took these medicines every day. The amount consumed (until 3 or more benzodiazepines per day) and concomitant use of other DIM were also higher. Women were the most frequent consumers, and anxiolytic use was usual. Consumption increases with age, but there were differences between men and women drivers from 60 years old. Conclusions: The current use of benzodiazepines must serve to awareness of the healthcare personnel, patients, and authorities on their risks, above all on the road safety.
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spelling pubmed-59330782018-05-11 The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study Herrera-Gómez, Francisco Gutierrez-Abejón, Eduardo Criado-Espegel, Paloma Álvarez, F. Javier Front Pharmacol Pharmacology Background: Benzodiazepines are driving-impairing medicines (DIM). This study presents current consumption of dispensed benzodiazepines in the Spanish general population, with a focus in pattern of use and concomitant medicines consumed with. Methods: A population-based registry study was carried out to assess the year-2016 granted benzodiazepines dispensation in Castile and León. Weighting was performed to obtain the adjusted benzodiazepine consumption for licensed drivers according to age and gender using our national drivers' license census data. Results: Benzodiazepines were used by 15.38% of the general population and 10.97% of drivers. Nearly 2% of the population and more than 1% of drivers took these medicines every day. The amount consumed (until 3 or more benzodiazepines per day) and concomitant use of other DIM were also higher. Women were the most frequent consumers, and anxiolytic use was usual. Consumption increases with age, but there were differences between men and women drivers from 60 years old. Conclusions: The current use of benzodiazepines must serve to awareness of the healthcare personnel, patients, and authorities on their risks, above all on the road safety. Frontiers Media S.A. 2018-04-26 /pmc/articles/PMC5933078/ /pubmed/29755352 http://dx.doi.org/10.3389/fphar.2018.00408 Text en Copyright © 2018 Herrera-Gómez, Gutierrez-Abejón, Criado-Espegel and Álvarez. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Herrera-Gómez, Francisco
Gutierrez-Abejón, Eduardo
Criado-Espegel, Paloma
Álvarez, F. Javier
The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title_full The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title_fullStr The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title_full_unstemmed The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title_short The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study
title_sort problem of benzodiazepine use and its extent in the driver population: a population-based registry study
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933078/
https://www.ncbi.nlm.nih.gov/pubmed/29755352
http://dx.doi.org/10.3389/fphar.2018.00408
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