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Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese

INTRODUCTION: Telaprevir, a reversible selective inhibitor of viral protease and a potential blocker of viral replication, is indicated for the treatment of hepatitis C virus genotype 1 infection. In this study, the pharmacokinetic profile, safety, and tolerability of telaprevir and the effect of fo...

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Detalles Bibliográficos
Autores principales: Choi, Yewon, Yoon, Seonghae, Matsumoto, Kyoko, Ohta, Yoshiyasu, Lee, SeungHwan, Yu, Kyung-Sang, Jang, In-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933357/
https://www.ncbi.nlm.nih.gov/pubmed/29750017
http://dx.doi.org/10.2147/DDDT.S148117