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Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes

Chromosome mis-segregation leads to aneuploidy, a condition in which cells harbor an imbalanced chromosome number. Several lines of evidence strongly indicate that aneuploidy triggers genome instability, ultimately generating cells with complex karyotypes that arrest their proliferation. Isolation a...

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Detalles Bibliográficos
Autores principales: Wang, Ruoxi W., MacDuffie, Emily, Santaguida, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933501/
https://www.ncbi.nlm.nih.gov/pubmed/29708530
http://dx.doi.org/10.3791/57215