PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms

Poly-β(1,6)-N-acetyl-D-glucosamine (PNAG) is a major biofilm component of many pathogenic bacteria. The production, modification, and export of PNAG in Escherichia coli and Bordetella species require the protein products encoded by the pgaABCD operon. PgaB is a two-domain periplasmic protein that co...

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Detalles Bibliográficos
Autores principales: Little, Dustin J., Pfoh, Roland, Le Mauff, François, Bamford, Natalie C., Notte, Christina, Baker, Perrin, Guragain, Manita, Robinson, Howard, Pier, Gerald B., Nitz, Mark, Deora, Rajendar, Sheppard, Donald C., Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933820/
https://www.ncbi.nlm.nih.gov/pubmed/29684093
http://dx.doi.org/10.1371/journal.ppat.1006998

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