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piRNA-mediated regulation of transposon alternative splicing in soma and germline

Transposable elements can drive genome evolution, but their enhanced activity is detrimental to the host and therefore must be tightly regulated(1). The piwi-interacting small RNAs (piRNAs) pathway is critically important for transposable element regulation, by inducing transcriptional silencing or...

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Detalles Bibliográficos
Autores principales: Teixeira, Felipe Karam, Okuniewska, Martyna, Malone, Colin D., Coux, Rémi-Xavier, Rio, Donald C., Lehmann, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933846/
https://www.ncbi.nlm.nih.gov/pubmed/29211718
http://dx.doi.org/10.1038/nature25018