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MPDZ promotes DLL4-induced Notch signaling during angiogenesis
Angiogenesis is coordinated by VEGF and Notch signaling. DLL4-induced Notch signaling inhibits tip cell formation and vessel branching. To ensure proper Notch signaling, receptors and ligands are clustered at adherens junctions. However, little is known about factors that control Notch activity by i...
Autores principales: | Tetzlaff, Fabian, Adam, M Gordian, Feldner, Anja, Moll, Iris, Menuchin, Amitai, Rodriguez-Vita, Juan, Sprinzak, David, Fischer, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933922/ https://www.ncbi.nlm.nih.gov/pubmed/29620522 http://dx.doi.org/10.7554/eLife.32860 |
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