Case of lipoatrophic diabetes induced by juvenile dermatomyositis

Lipodystrophy is a rare condition that is often accompanied by one or more metabolic diseases. Here, we report a case of lipoatrophic diabetes induced by juvenile dermatomyositis. Although pioglitazone was not effective for lowering blood glucose levels, our observation suggested that it improved li...

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Autores principales: Baba, Yusuke, Kaneko, Hiyori, Takemoto, Minoru, Ide, Kana, Haga, Yuki, Kanda, Tatsuo, Akita, Shinsuke, Kubota, Yoshitaka, Kuroda, Masayuki, Kitagawa, Yutaka, Yokote, Koutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934268/
https://www.ncbi.nlm.nih.gov/pubmed/28895299
http://dx.doi.org/10.1111/jdi.12745
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author Baba, Yusuke
Kaneko, Hiyori
Takemoto, Minoru
Ide, Kana
Haga, Yuki
Kanda, Tatsuo
Akita, Shinsuke
Kubota, Yoshitaka
Kuroda, Masayuki
Kitagawa, Yutaka
Yokote, Koutaro
author_facet Baba, Yusuke
Kaneko, Hiyori
Takemoto, Minoru
Ide, Kana
Haga, Yuki
Kanda, Tatsuo
Akita, Shinsuke
Kubota, Yoshitaka
Kuroda, Masayuki
Kitagawa, Yutaka
Yokote, Koutaro
author_sort Baba, Yusuke
collection PubMed
description Lipodystrophy is a rare condition that is often accompanied by one or more metabolic diseases. Here, we report a case of lipoatrophic diabetes induced by juvenile dermatomyositis. Although pioglitazone was not effective for lowering blood glucose levels, our observation suggested that it improved liver function slightly. The effectiveness of metreleptin for lowering blood glucose levels could not be determined, as we administered it in a short period. Liver biopsy showed burned‐out non‐alcoholic steatohepatitis. The present results show that the successful treatment of lipoatrophic diabetes induced by juvenile dermatomyositis requires an early diagnosis and therapeutic intervention.
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spelling pubmed-59342682018-05-10 Case of lipoatrophic diabetes induced by juvenile dermatomyositis Baba, Yusuke Kaneko, Hiyori Takemoto, Minoru Ide, Kana Haga, Yuki Kanda, Tatsuo Akita, Shinsuke Kubota, Yoshitaka Kuroda, Masayuki Kitagawa, Yutaka Yokote, Koutaro J Diabetes Investig Articles Lipodystrophy is a rare condition that is often accompanied by one or more metabolic diseases. Here, we report a case of lipoatrophic diabetes induced by juvenile dermatomyositis. Although pioglitazone was not effective for lowering blood glucose levels, our observation suggested that it improved liver function slightly. The effectiveness of metreleptin for lowering blood glucose levels could not be determined, as we administered it in a short period. Liver biopsy showed burned‐out non‐alcoholic steatohepatitis. The present results show that the successful treatment of lipoatrophic diabetes induced by juvenile dermatomyositis requires an early diagnosis and therapeutic intervention. John Wiley and Sons Inc. 2017-12-01 2018-05 /pmc/articles/PMC5934268/ /pubmed/28895299 http://dx.doi.org/10.1111/jdi.12745 Text en © 2017 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Articles
Baba, Yusuke
Kaneko, Hiyori
Takemoto, Minoru
Ide, Kana
Haga, Yuki
Kanda, Tatsuo
Akita, Shinsuke
Kubota, Yoshitaka
Kuroda, Masayuki
Kitagawa, Yutaka
Yokote, Koutaro
Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title_full Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title_fullStr Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title_full_unstemmed Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title_short Case of lipoatrophic diabetes induced by juvenile dermatomyositis
title_sort case of lipoatrophic diabetes induced by juvenile dermatomyositis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934268/
https://www.ncbi.nlm.nih.gov/pubmed/28895299
http://dx.doi.org/10.1111/jdi.12745
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