Architecture of an HIV-1 reverse transcriptase initiation complex

Reverse transcription of the HIV-1 RNA genome into double-stranded DNA is a central step in infection(1) and a common target of antiretrovirals(2). The reaction is catalyzed by viral reverse transcriptase (RT)(3,4) that is packaged in an infectious virion along with 2 copies of dimeric viral genomic...

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Detalles Bibliográficos
Autores principales: Larsen, Kevin P., Mathiharan, Yamuna Kalyani, Kappel, Kalli, Coey, Aaron, Chen, Dong-Hua, Barrero, Daniel, Madigan, Lauren, Puglisi, Joseph D., Skiniotis, Georgios, Puglisi, Elisabetta Viani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934294/
https://www.ncbi.nlm.nih.gov/pubmed/29695867
http://dx.doi.org/10.1038/s41586-018-0055-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934294/
https://www.ncbi.nlm.nih.gov/pubmed/29695867
http://dx.doi.org/10.1038/s41586-018-0055-9

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