CCDC102B confers risk of low vision and blindness in high myopia

The incidence of high myopia is increasing worldwide with myopic maculopathy, a complication of myopia, often progressing to blindness. Our two-stage genome-wide association study of myopic maculopathy identifies a susceptibility locus at rs11873439 in an intron of CCDC102B (P = 1.77 × 10(−12) and P...

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Detalles Bibliográficos
Autores principales: Hosoda, Yoshikatsu, Yoshikawa, Munemitsu, Miyake, Masahiro, Tabara, Yasuharu, Shimada, Noriaki, Zhao, Wanting, Oishi, Akio, Nakanishi, Hideo, Hata, Masayuki, Akagi, Tadamichi, Ooto, Sotaro, Nagaoka, Natsuko, Fang, Yuxin, Ohno-Matsui, Kyoko, Cheng, Ching-Yu, Saw, Seang Mei, Yamada, Ryo, Matsuda, Fumihiko, Tsujikawa, Akitaka, Yamashiro, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934384/
https://www.ncbi.nlm.nih.gov/pubmed/29725004
http://dx.doi.org/10.1038/s41467-018-03649-3

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