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A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are an important family of natural products. Their biosynthesis follows a common scheme in which the leader peptide of a precursor peptide guides the modifications of a single core peptide. Here we describe biochemical studie...
Autores principales: | Zhang, Yi, Li, Kunhua, Yang, Guang, McBride, Joshua L., Bruner, Steven D., Ding, Yousong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934393/ https://www.ncbi.nlm.nih.gov/pubmed/29725007 http://dx.doi.org/10.1038/s41467-018-04154-3 |
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