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Top-down beta oscillatory signaling conveys behavioral context in early visual cortex

Top-down modulation of sensory processing is a critical neural mechanism subserving numerous important cognitive roles, one of which may be to inform lower-order sensory systems of the current ‘task at hand’ by conveying behavioral context to these systems. Accumulating evidence indicates that top-d...

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Autores principales: Richter, Craig G., Coppola, Richard, Bressler, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934398/
https://www.ncbi.nlm.nih.gov/pubmed/29725028
http://dx.doi.org/10.1038/s41598-018-25267-1
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author Richter, Craig G.
Coppola, Richard
Bressler, Steven L.
author_facet Richter, Craig G.
Coppola, Richard
Bressler, Steven L.
author_sort Richter, Craig G.
collection PubMed
description Top-down modulation of sensory processing is a critical neural mechanism subserving numerous important cognitive roles, one of which may be to inform lower-order sensory systems of the current ‘task at hand’ by conveying behavioral context to these systems. Accumulating evidence indicates that top-down cortical influences are carried by directed interareal synchronization of oscillatory neuronal populations, with recent results pointing to beta-frequency oscillations as particularly important for top-down processing. However, it remains to be determined if top-down beta-frequency oscillations indeed convey behavioral context. We measured spectral Granger Causality (sGC) using local field potentials recorded from microelectrodes chronically implanted in visual areas V1/V2, V4, and TEO of two rhesus macaque monkeys, and applied multivariate pattern analysis to the spatial patterns of top-down sGC. We decoded behavioral context by discriminating patterns of top-down (V4/TEO-to-V1/V2) beta-peak sGC for two different task rules governing correct responses to identical visual stimuli. The results indicate that top-down directed influences are carried to visual cortex by beta oscillations, and differentiate task demands even before visual stimulus processing. They suggest that top-down beta-frequency oscillatory processes coordinate processing of sensory information by conveying global knowledge states to early levels of the sensory cortical hierarchy independently of bottom-up stimulus-driven processing.
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spelling pubmed-59343982018-05-10 Top-down beta oscillatory signaling conveys behavioral context in early visual cortex Richter, Craig G. Coppola, Richard Bressler, Steven L. Sci Rep Article Top-down modulation of sensory processing is a critical neural mechanism subserving numerous important cognitive roles, one of which may be to inform lower-order sensory systems of the current ‘task at hand’ by conveying behavioral context to these systems. Accumulating evidence indicates that top-down cortical influences are carried by directed interareal synchronization of oscillatory neuronal populations, with recent results pointing to beta-frequency oscillations as particularly important for top-down processing. However, it remains to be determined if top-down beta-frequency oscillations indeed convey behavioral context. We measured spectral Granger Causality (sGC) using local field potentials recorded from microelectrodes chronically implanted in visual areas V1/V2, V4, and TEO of two rhesus macaque monkeys, and applied multivariate pattern analysis to the spatial patterns of top-down sGC. We decoded behavioral context by discriminating patterns of top-down (V4/TEO-to-V1/V2) beta-peak sGC for two different task rules governing correct responses to identical visual stimuli. The results indicate that top-down directed influences are carried to visual cortex by beta oscillations, and differentiate task demands even before visual stimulus processing. They suggest that top-down beta-frequency oscillatory processes coordinate processing of sensory information by conveying global knowledge states to early levels of the sensory cortical hierarchy independently of bottom-up stimulus-driven processing. Nature Publishing Group UK 2018-05-03 /pmc/articles/PMC5934398/ /pubmed/29725028 http://dx.doi.org/10.1038/s41598-018-25267-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Richter, Craig G.
Coppola, Richard
Bressler, Steven L.
Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title_full Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title_fullStr Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title_full_unstemmed Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title_short Top-down beta oscillatory signaling conveys behavioral context in early visual cortex
title_sort top-down beta oscillatory signaling conveys behavioral context in early visual cortex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934398/
https://www.ncbi.nlm.nih.gov/pubmed/29725028
http://dx.doi.org/10.1038/s41598-018-25267-1
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