A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression

In chronic lymphocytic leukemia (CLL), the non-hematopoietic stromal microenvironment plays a critical role in promoting tumor cell recruitment, activation, survival, and expansion. However, the nature of the stromal cells and molecular pathways involved remain largely unknown. Here, we demonstrate...

Descripción completa

Detalles Bibliográficos
Autores principales: Farinello, Diego, Wozińska, Monika, Lenti, Elisa, Genovese, Luca, Bianchessi, Silvia, Migliori, Edoardo, Sacchetti, Nicolò, di Lillo, Alessia, Bertilaccio, Maria Teresa Sabrina, de Lalla, Claudia, Valsecchi, Roberta, Gleave, Sabrina Bascones, Lligé, David, Scielzo, Cristina, Mauri, Laura, Ciampa, Maria Grazia, Scarfò, Lydia, Bernardi, Rosa, Lazarevic, Dejan, Gonzalez-Farre, Blanca, Bongiovanni, Lucia, Campo, Elias, Cerutti, Andrea, Ponzoni, Maurilio, Pattini, Linda, Caligaris-Cappio, Federico, Ghia, Paolo, Brendolan, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934403/
https://www.ncbi.nlm.nih.gov/pubmed/29725010
http://dx.doi.org/10.1038/s41467-018-04150-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934403/
https://www.ncbi.nlm.nih.gov/pubmed/29725010
http://dx.doi.org/10.1038/s41467-018-04150-7

Ejemplares similares