A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression

In chronic lymphocytic leukemia (CLL), the non-hematopoietic stromal microenvironment plays a critical role in promoting tumor cell recruitment, activation, survival, and expansion. However, the nature of the stromal cells and molecular pathways involved remain largely unknown. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Farinello, Diego, Wozińska, Monika, Lenti, Elisa, Genovese, Luca, Bianchessi, Silvia, Migliori, Edoardo, Sacchetti, Nicolò, di Lillo, Alessia, Bertilaccio, Maria Teresa Sabrina, de Lalla, Claudia, Valsecchi, Roberta, Gleave, Sabrina Bascones, Lligé, David, Scielzo, Cristina, Mauri, Laura, Ciampa, Maria Grazia, Scarfò, Lydia, Bernardi, Rosa, Lazarevic, Dejan, Gonzalez-Farre, Blanca, Bongiovanni, Lucia, Campo, Elias, Cerutti, Andrea, Ponzoni, Maurilio, Pattini, Linda, Caligaris-Cappio, Federico, Ghia, Paolo, Brendolan, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934403/
https://www.ncbi.nlm.nih.gov/pubmed/29725010
http://dx.doi.org/10.1038/s41467-018-04150-7

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